Prion Alliance is a 501(c)(3) non-profit devoted exclusively to advancing scientific research towards a treatment or cure for human prion disease — a fatal neurodegenerative diseases caused by misfolded proteins and known by various names including as Creutzfeldt-Jakob disease, fatal familial insomnia, and Gerstmann-Sträussler-Scheinker disease. At present, there is no treatment or cure.
We — Sonia Vallabh and Eric Minikel — founded Prion Alliance after we learned in 2011 that Sonia inherited a genetic mutation that causes prion disease. We changed our careers to become scientists and devote our lives to a cure. We earned our PhDs at Harvard Medical School and established a prion laboratory at the Broad Institute of MIT and Harvard, where we work on developing therapeutics for human prion disease.
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