Prion Alliance is a 501(c)(3) non-profit devoted exclusively to advancing scientific research towards a treatment or cure for human prion disease. Prion diseases are fatal neurodegenerative diseases caused by misfolded proteins and known by various names, such as Creutzfeldt-Jakob disease, fatal familial insomnia, and Gertsmann-Sträussler-Scheinker disease. At present, there is no treatment or cure. We — Sonia Vallabh and Eric Minikel — founded Prion Alliance as part of our scientific quest after we learned in 2011 that Sonia inherited a genetic mutation that causes prion disease. We recently defended our PhDs at Harvard Medical School, and now run a prion laboratory at the Broad Institute of MIT and Harvard, where we work on developing therapeutics for human prion disease.

You can donate via PayPal to support our quest:

To learn more about our story, read one of these articles:

Or watch this talk:

Also, here are some handy facts about Prion Alliance:

  • Prion Alliance was founded in June 2012 and received 501(c)(3) determination in October 2012.
  • Board members: Sonia Vallabh (President), Eric Minikel, Greta Beekhuis
  • Federal Tax ID (or EIN, for deducting your donation): 46-0732060
  • You can find official forms and documents on Prion Alliance here.